noun. undefined

adjective. Opiate.

noun. A substance that is like opium.

noun. Any of the natural substances, such as an endorphin, released in the body in response to pain.

noun. Any of a group of synthetic compounds that exhibit similarities to the opium alkaloids that occur in nature.

""There is little evidence that long-term opioid use is efficacious in reducing pain, much less in restoring function, the true goal of treatment," Seth Berkowitz and Mitchell Katz, physicians at the Los Angeles County Department of Health Services, wrote in"