WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
noun.
(medicine) a malignant state; progressive and resistant to treatment and tending to cause death
noun.
quality of being disposed to evil; intense ill will
Word Usage
"Before there was suspicion, with the citation of his criminal behavior and apparent lack of remorse and contrition and humility etc., there is proof of at least past malignance."