To poison with the loco-weed or crazy-weed.

noun. Same as loco-weed.

noun. A disease of animals resulting from eating loco-weeds.

Derived from loco-weed.

noun. An abbreviated form of locomotive.

Hence To make crazy or in any way eccentric: as, he's plumb locoed.

adverb. A direction in written or printed music to return to the proper pitch after having played an octave higher.

noun. A plant (Astragalus Hornii) growing in the Southwestern United States, which is said to poison horses and cattle, first making them insane. The name is also given vaguely to several other species of the same genus. Called also loco weed.

noun. Any one of various leguminous plants or weeds besides Astragalus, whose herbage is poisonous to cattle, as Spiesia Lambertii, syn. Oxytropis Lambertii.

noun. A locomotive.

transitive verb. To poison with loco; to affect with the loco disease; hence (Colloq.), to render insane or mad.

adjective. Insane; crazy.

adverb. A direction in written or printed music to return to the proper pitch after having played an octave higher or lower.

noun. locomotive

adjective. crazy

adjective. intoxicated by eating locoweed

noun. certain species of Astragalus or Oxytropis, capable of causing locoism.

adjective. informal or slang terms for mentally irregular