noun. The degree to which or rate at which a drug or other substance is absorbed or becomes available at the site of physiological activity after administration.

noun. The amount of drug which reaches the site of physiological activity after administration.

"Oral doses are rapidly and completely absorbed, with peak levels reached after 29 to 90 minutes; however, bioavailability is low due to a hepatic first-pass effect. 6 The pharmacokinetics are not significantly affected by gender, age, renal failure or hemodialysis beginning one hour after drug administration."

bio-unavailable  

and  anticoagulants  anticoagulation  carcinogenicity  carry-over